| 1980 Trades | |||||
| 1 | To Homestead: | Steve Stone | 1 | To St Louis: | Joe Sambito |
| 2 | To Durham: | Homestead's 1st rd pick in '81 | 2 | To Homestead: | Lou Piniella & Larry Hisle |
| 3 | To St Louis: | Ben Oglivie | 3 | To New York: | St Louis' 1st rd pick in '80 & 2nd rd pick in '81 |
| 4 | To Reading: | Reggie Cleveland | 4 | To Kansas City: | Reading's 5th & 8th rd picks in '81 |
| 5 | To Reading: | Moose Haas | 5 | To New York: | Reading's 2nd rd pick in '80 |
| 6 | To Niagara Falls: | Hal McRae & Homestead's 2nd rd pick in '80 | 6 | To Durham: | Sioux Falls' 1st rd pick in '80 & Niagara Falls' 1st rd pick in '81 |
| 7 | To Reading: | Neil Allen & Philadelphia's 3rd rd pick in '80 | 7 | To Sacramento: | Reading's 1st rd pick in '80 |
| 8 | To St Louis: | Dan Ford & Sioux Falls' 2nd rd pick in '81 | 8 | To Sioux Falls: | St Louis' 2nd rd pick in '80 |
| 9 | To Sacramento: | Willie Wilson & Kansas City's 7th rd pick in '81 | 9 | To Kansas City: | Charlie Hough & Sacramento's 3rd rd pick in '81 |
| 10 | To Houston: | Rick Wise | 10 | To Reading: | Houston's 4th rd pick in '80 |
| 11 | To Kansas City: | Don Baylor | 11 | To Baltimore: | Richie Zisk |
| 12 | To Sioux Falls: | Sioux Falls' 4th rd pick in '80 | 12 | To Kansas City: | Sioux Falls' 6th rd pick in '80 & 4th rd pick in '81 |
| 13 | To New York: | Homestead's 4th rd pick in '81 | 13 | To Homestead: | Columbus' 5th rd pick in '80 |
| 14 | To Kansas City: | St Louis' 7th & 8th rd picks in '80 and 4th & 5th rd picks in '81 | 14 | To St Louis: | Kansas City's 5th rd pick in '80, 9th & 10th rd picks in '81 and Hollywood's 5th rd pick in '80 |
| 15 | To Durham: | Bill North | 15 | To Philadelphia: | Durham's 6th rd pick in '80 & '81 |
| 16 | To Hollywood: | St Louis' 6th rd pick in '80 | 16 | To St Louis: | Hollywood's 5th rd pick in '81 |
| 17 | To Baltimore: | Dan Ford | 17 | To St Louis: | Baltimore's 5th rd pick in '81 |
| 18 | To Baltimore: | Bismarck's 5th rd pick in '81 | 18 | To Bismarck: | Baltimore's 6th & 12th rd picks in '80 |
| 19 | To Bismarck: | Sioux Falls' 6th rd pick in '80 | 19 | To Kansas City: | Bismarck's 8th rd pick in '80 & 6th rd pick in '81 |
| 20 | To Niagara Falls: | Jim Spencer | 20 | To Hollywood: | Niagara Falls' 7th rd pick in '80 |
| 21 | To Homestead: | Tom Burgmeier | 21 | To River City: | Dave Rozema |
| 22 | To St Paul: | Ron Cey & Bismarck's 5th rd pick in '81 | 22 | To Baltimore: | Wayne Gross & St Paul's 1st rd pick in '81 |
| 23 | To Homestead: | Dennis Kinney & Dyar Miller | 23 | To Kansas City: | Craig Swan & Mike Proly |
| 24 | To Bismarck: | Dave Kingman, Brian Kingman and Baltimore's 6th & 7th rd poicks in '81 | 24 | To Baltimore: | Bismarck's 2nd & 3rd rd picks in '81 |
| 25 | To Baltimore: | Homestead's 2nd rd pick in '81 | 25 | To Homestead: | Lee Mazzilli |
| 26 | To St Paul: | Clint Hurdle | 26 | To Niagara Falls: | Jerry Royster |
| 27 | To Reading: | Eric Soderholm & Rafael Landestoy | 27 | To Houston: | Cliff Johnson & Reading's 4th rd pick in '81 |
| 28 | To Sioux Falls: | Tom Seaver | 28 | To Houston: | Sioux Falls' 1st rd pick in '81 |
| 29 | To Reading: | Enrique Romo | 29 | To St Paul: | Kevin Saucier |
| 30 | To St Paul: | Sioux Falls' 6th rd pick in '81 | 30 | To Sioux Falls: | Jim Wohlford |
| 31 | To Sioux Falls: | Bill North & Durham's 5th rd pick in '81 | 31 | To Durham: | Sioux Falls' 3rd rd pick in '81 |
| 32 | To Philadelphia: | Art Howe, Mike Proly & Reading's 8th rd pick in '81 | 32 | To Kansas City: | Philadelphia's 3rd rd pick in '81 |
| 33 | To Sacramento: | Houston's 3rd rd pick in '81 | 33 | To Houston: | Mookie Wilson |